Longitudinal Data Observed over Unequal Time Intervals: Modeling Correlations in the Analysis of Binary Outcomes Data - Soe Soe Thwin - Bücher - VDM Verlag Dr. Müller - 9783639110142 - 19. Dezember 2008
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Longitudinal Data Observed over Unequal Time Intervals: Modeling Correlations in the Analysis of Binary Outcomes Data

Soe Soe Thwin

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Longitudinal Data Observed over Unequal Time Intervals: Modeling Correlations in the Analysis of Binary Outcomes Data

This monograph extends previous work on the evaluation of GEE performance in parameter estimation with correlation structure misspecification. It examines a new structure to model the correlation between binary responses observed over unequal time intervals. The proposed unequal-time correlation structure accounts for unequal intervals by fixing the correlation coefficient and interval length between the first 2 observations and by adjusting the correlations for subsequent pairs by their relative interval length. To evaluate this structure, correlated binary responses under the logistic model were generated with the unequal time correlation structure for a full range of positive correlations and strength of association under different scenarios of number of measurements, sample size and prevalence of exposure. The model was evaluated when the working correlation structure was misspecified as exchangeable, 1st order autoregressive, unstructured, or when alternating logistic regression was employed.

Medien Bücher     Taschenbuch   (Buch mit Softcover und geklebtem Rücken)
Erscheinungsdatum 19. Dezember 2008
ISBN13 9783639110142
Verlag VDM Verlag Dr. Müller
Seitenanzahl 252
Maße 340 g
Sprache Englisch